Pericardial Effusion Revealing Cardiac and Thyroid AA Amyloidosis in Chronic Inflammatory Bowel Disease Complicated by Hypothyroidism Discovered Incidentally
Published: 2024-03-28
Page: 42-46
Issue: 2024 - Volume 7 [Issue 1]
Bettar Mohamed Ghoulame *
Department of Cardiology, Ibn Rochd University Hospital, Casablanca, Morocco.
M. Njie
Department of Cardiology, Ibn Rochd University Hospital, Casablanca, Morocco.
J. Moyambe
Department of Cardiology, Ibn Rochd University Hospital, Casablanca, Morocco.
Charfo B Mahamado
Department of Cardiology, Ibn Rochd University Hospital, Casablanca, Morocco.
Haboub Mérieme
Faculty of Medicine and Pharmacy of Casablanca, Morocco.
Arous Salim
Faculty of Medicine and Pharmacy of Casablanca, Morocco.
Med Ghali Bennouna
Faculty of Medicine and Pharmacy of Casablanca, Morocco.
Rachida Habbal
Faculty of Medicine and Pharmacy of Casablanca, Morocco.
*Author to whom correspondence should be addressed.
Abstract
The association of pericardial effusion with ventricular hypertrophy is one of the signs suggestive of cardiac amyloidosis, according to the literature. We report a case of cardiac and thyroid AA amyloidosis in a 65-year-old patient followed for chronic inflammatory bowel disease complicated by hypothyroidism revealed by a large pericardial effusion. We report a case of a 65-year-old postmenopausal patient followed for constipation for 3 years without any other particular history, who consulted for dyspnea evolving for 20 days initially with effort then becoming at rest evolving in a context of alteration of the general condition. Our report is the case of type AA amyloidosis probably secondary to chronic intestinal inflammation responsible for cardiac damage expressed by left ventricular hypertrophy and thyroid damage leading to hypothyroidism responsible for large pericardial effusion.
Keywords: Pericardial effusion, AA amyloidosis, hypothyroidism
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References
Lachmann HJ, Goodman HJB, Gilbertson JA, Gallimore JR, Sabin CA, Gillmore JD et al. Natural history and outcome in systemic AA Amyloidosis. N Engl J Med. 7 Juin 2007;356(23):2361-71.
Zimmerman J, Yahalom J, Bar-On H. Clinical spectrum of pericardial effusion as the presenting feature of hypothyroidism. Am heart J. 1983;106:770-771.
Lin CT, Liu CJ, Lin TK, Chen CW, Chen BC, Lin CL. Myxedema associated with cardiac tamponase. Jpn Heart J. 2003;44(3):447–50. [PubMed] [Google Scholar]
Sagristà-Sauleda J, Mercé J, Permanyer-Miralda G, Soler-Soler J. Clinical clues to the causes of large pericardial effusion. Am J Med. 2000;109(2):95–101. [PubMed] [Google Scholar],
Zoubeidi H, Aydi Z, Daoud F, Baili L, Ben Dhaou B, Boussema F. Cardiac manifestations during hypothyroidism: Series of 16 cases, Annals of Endocrinology. 2014;75(5–6):501.
ISSN 0003-4266.
Echocardiographic caracterisation of the reversible cardiomyopathy of hypothyroidism; AD santos et al. Am J Med ;1980 May.
Bodez D, Guendouz S, Grateau G, Galat A, Avellino V, Kharoubi M, Guellich A, Urbanski G, Itti E, Deux JF, Damy T, Georgin Lavialle S. Cardiac involvement in AA amyloidosis: Prospective study on 38 patients, La Revue de Médecine Interne. 2017;38(2):A67-A68.
ISSN 0248-8663.
In Boudjema, hypothyroidism in type AA amyloidosis, think of thyroid amyloidosis even in the absence of goiter. Khan. Revue d’Endocrinologie; 2008.