Asian Journal of Cardiology Research <p style="text-align: justify;"><strong>Asian Journal of Cardiology Research</strong>&nbsp;aims to publish&nbsp;high-quality&nbsp;papers (<a href="/index.php/AJCR/general-guideline-for-authors">Click here for Types of paper</a>) in all areas of&nbsp;‘Cardiology research’. This journal facilitates the research and wishes to publish papers as long as they are technically correct, scientifically motivated. The journal also encourages the submission of useful reports of negative results. This is a quality controlled,&nbsp;OPEN&nbsp;peer-reviewed, open access INTERNATIONAL journal.</p> en-US (Asian Journal of Cardiology Research) (Asian Journal of Cardiology Research) Wed, 09 Dec 2020 07:17:35 +0000 OJS 60 Silver Nanoparticles Induced Cardiac Toxicity <p><strong>Aim: </strong>Silver nanoparticles (Ag NPs) have been utilized in a wide assortment of uses as antimicrobial specialists and have been fused into a few items as mechanical and food items not withstanding natural and clinical applications. Inordinate utilization of nanoparticles might be dangerous to human wellbeing and the climate. No sufficient information present about the toxic effect of silver nanoparticles on heart. Accordingly, The current study aimed to investigate the cardiac toxicity of silver nanoparticles.</p> <p><strong>Study Design:</strong> A total 20 male Wistar rats were divided into 2 equivalent groups (Group 1, control; group 2, Ag NPs).</p> <p><strong>Results:</strong> Current results revealed that; Ag NPs induced a significant decrease in serum e kinase myoglobin (CK-MB), phosphokinase (CPK), myoglobin, alkaline phosphatase (ALP) and aspartate aminotransferase (AST), cholesterol, triglycerides, and low-density lipids (LDL) while they cause a significant depletion in the levels of high-density lipids (HDL) in the sera of Ag NPs group (Gp2) when compared with the control group (Gp1).</p> <p><strong>Conclusion:</strong> The present study confirmed that; silver nanoparticles (Ag NPs) induced cardiac toxicity in rats.</p> Yasmeen M. Amer, Afaf Elatrash, Ehab Tousson ##submission.copyrightStatement## Mon, 11 Jan 2021 00:00:00 +0000 Blood Oxygen Saturation and Prolong Face Mask Use in Healthcare Workers in Port Harcourt Nigeria, in the COVID 19 Pandemic Era <p><strong>Introduction: </strong>The World Health Organization (WHO) declared the Corona Virus disease 2019 (COVID 19) caused by Severe Acute Respiratory Syndrome Corona Virus 2(SARS-Cov-2) a pandemic in March 2020. Aerosolized infected droplets and airborne transmission have been proffered as means of transmission, and as such, the use of face masks has been advocated as a key strategy in the disease control - more so in health care workers who are at the fore-front of the pandemic. However, the use of face masks for prolonged periods has raised concerns on possible adverse effect on blood oxygenation, potentially affecting compliance.</p> <p><strong>Aim:</strong> To monitor the blood oxygen saturation (SPO<sub>2</sub>) of healthcare workers wearing facemasks for 8-hours in the course of their duties, in a tertiary institution in Port Harcourt, Nigeria.</p> <p><strong>Methods:</strong> A cross-sectional study of healthcare workers wearing face masks while working. Baseline pre-face mask use SPO<sub>2</sub> was done at Zero hour. Subsequently, serial hourly SPO<sub>2</sub> were recorded until completion at the eight-hour. The respiratory and pulse rates were recorded at zero and eight hours. The results were analysed and presented as Means, Medians, Graphs and Tables.</p> <p><strong>Results:</strong> There were 220 participants with more females 147(66.8%). Doctors constituted 133(60.5%). The baseline pre-facemask Mean SPO<sub>2</sub> was 97.9% ±0.75. The Median SPO<sub>2</sub> was 98%. The overall SPO<sub>2</sub> trend across 8 hours was maintained above 97.7% for all participants. Age was significantly associated with differences in SPO<sub>2</sub> trend (P=0.032) (P=006); while Type of Facemask use had no significant effect on mean SPO<sub>2</sub> trend (p=1.00). There was no significant difference in respiratory and pulse rates pre and post 8-hours face mask use.</p> <p><strong>Conclusion: </strong>Healthcare workers using facemasks continuously over eight hours maintained normal SPO<sub>2</sub> level, with physiologic adaptation of respiratory and pulse rates.</p> Petronila N. Tabansi, Uchenna Onubogu ##submission.copyrightStatement## Wed, 09 Dec 2020 00:00:00 +0000